How psilocybin derived from (magic) mushroom spores affect the brain

Warning: Doctors strongly advise against the unregulated use of illicit drugs. But they are free to prescribe similar substances, but only after having a consultation to ascertain the suitability of the treatment for their patient. You are free to get a second opinion and decide what is best for you. So explore all the options and ask yourself if drugs help to nourish and detoxify a sick brain? Why take a substance if you can control your own mind and learn to resonate with your higher self on a permanent basis. Becoming a drug addict is not really the solution to depression and self-hatred.

A sound mind in a healthy body is a happy home for all you are!
Be healthy and happy – no excuses and no drugs

Introducing magic mushrooms? I was asked to discuss magic mushrooms with Shado Twala on the radio after we heard about the arrest of a woman in Somerset West found to be in possession of illegal drugs. She was having a ceremony in her house to enlighten and take her guests to “higher levels of consciousness.” The police confiscated bundles of marijuana and a pack of magic mushrooms. One of her guests had a panic attack and raised the alarm. If these magic mushrooms are so harmless and able to make people feel good then what is the problem? Like any drug, illegal or medically prescribed there are reasons people take them and there are a lot of contra indications and harmful – if not fatal side effects. To self-medicate is one thing, to involve people who may be medically unfit is another.

Over 200 species of mushrooms contain the drug psilocybin in their spores. They are said to produce colourful hallucinations, even when consumed in small quantities. But similar looking mushrooms are poisonous and can cause a terminal trip – they will kill you! It is advisable to stay away from a substance that people rave about until you know the whole truth about it. Even then, ask yourself if the drug will help you heal a brain that may already be overburdened by heavy metals, mycotoxins (the toxic exudations of yeast, mould and fungi) and amyloid plaque (from a bad diet) that accumulate and can cause neurological disorders, including depression and dementia.
Do pharmaceutical or recreational drugs ever deal with the real cause of the problem?

Smoking marijuana (dagga) destroys the protective effects of the blood brain barrier and thus more toxins and foreign substances can damage brain tissue. Excessive exposure to cell phones, heavy metals, environmental toxins and wireless devices do the same thing. They open up the channels and the brain becomes overloaded with toxins. As a result people become brain-sick. They get depressed, obsessive, attention deficit, brain foggy, socially uncomfortable and seek a form of relief.

Anything that affects the brain and alters your behaviour is suspect. So why do people feel the need to hallucinate – to trip out on illegal drugs and then say that they are enlightened? They live in an unhealthy body that is malnourished; they lack fresh air, exercise and sunshine and then wonder why they feel so miserable, depressed and shut out of life? After the surge of elation they are worse off, having had a taste of what they call the higher self. It is hard to believe that the magic mushroom practice is not habit forming. Don’t kid yourself. People can’t leave dagga, magic mushrooms and other mind bending substances alone because the brain stops generating its own feel good chemicals if you introduce them from another source.
Magic mushrooms take their toll

If you are taking drugs that behave like psilocybin you are worse off because these chemicals flood into the brain and deactivate sections of it that are said to be overactive in depressed people. But why are brain tissues overactive in the first place? We need to look at the causes of a sick, toxic brain. Our blood-brain barrier is supposed to protect us from environmental poisons, heavy metals, radiation, toxins and especially microbial infections. Mould and fungal infections (including mushrooms) can generate mycotoxins. These toxic substances cause inflammation in the brain and in most cases of cancer you will find them present in brain tumours.
Take a ride but who takes control?

Sue: The brain requires greater quantities of any replacement (or interfering) chemical you introduce it to as a drug. It may be an antidepressant, a sleeping pill, a prescribed psychiatric drug or a narcotic. They are all habit forming and can have dangerous side effects. Even woo-woo drugs will not help to detoxify or nourish a badly damaged, overburdened and malnourished brain. How can you have a sound mind in an unhealthy body?
Would your Doctor prescribe psilocybin? Maybe

Research published in the British Journal of Psychiatry in 2012 found that volunteers taking psilocybin had enhanced recall. They are considering it as an effective adjunct to psychotherapy. Another 2012 study, published in the Proceedings of the National Academy of Sciences, found that the drug slowed activity in the centres of the brain that are hyperactive in people with depression. There’s also some evidence that small amounts of psilocybin can relieve the symptoms of cluster headaches, obsessive-compulsive disorder, drug and alcohol dependence and depression. But there are side effects to consider. The drug does not detoxify the brain or supply any suitable nutrients to sustain an on-going supply of serotonin to correct the underlying sense of self hatred, depression, drug addiction, alcoholism or feelings of gloom and doom, suicide, boredom or apathy.
Scientific studies of the effects of psilocybin

Psilocybin can produce perceptual distortions (visual or auditory). People say that they can “see” music or “hear” colours because sensory perceptions are confused. Users may also experience hallucinations and a loss of touch with reality. Psilocybin can also cause a person to feel anxious and have panic attacks. But some people say the experience transforms their lives for the better and claim it has a lasting effect. We cannot judge anybody and are happy for a positive outcome but according to scientific investigations. But this is not always the case because the opposite effect is also possible. The outcome cannot be established until the drug has been taken.
Unfortunately, as with most hallucinogenic drugs, the effects of magic mushrooms are unreliable and unpredictable. Nothing to hang your hopes on and some trips take a turn for the worse. Behaviour may include odd reactions to normal events, distinct outbursts and panic attacks. Some users will experience a spiritual aha, become enlightened and meet their maker. But others may freak out with extreme fits of paranoia, anxiety and schizophrenic or chaotic outbursts.
Effects on serotonin – disruption

MRI brain scans showed that psilocybin decreases activity across the thalamus that divides the two hemispheres of the brain. This makes imagination more vivid and animated and the world is experienced as unusual. Psilocybin mimics the effect of serotonin a neurotransmitter that generates a feeling of relaxation and wellbeing. In the brain, psilocybin latches onto serotonin receptors and has a calming effect. They are overactive in depressed patient so this drug is already being considered as an alternative treatment for depression. The effect lasts about a half-hour for a moderate dose given as an intravenous shot. But herbs such as St John’s Wort, tryptophan and supplements containing vitamin B complex, Omega 3 oil and tyrosine do that without side effects.

Professional opinions: “There is increasing evidence that the regions affected are responsible for giving us our sense of self,” claims Robin Carhart-Harris, a postdoctoral researcher at the Imperial College of London. “Healthy people given psilocybin often describe their experiences as among the most meaningful of their whole lives, comparable to such things as the birth of their first child or getting married”

“In other words, the regions affected make up what some people call our ‘ego.’ That activity decreases in the ‘ego-network’ supports what people often say about psychedelics, that they temporarily ‘dissolve the ego.’ Is the opinion of enthusiastic pro-hallucinatory investigators?
What about drug dependence and tripping?

Like other types of hallucinogenic drugs, psilocybin can produce a wide range of euphoric and psychedelic effects. Psilocybin can produce elation, hallucinations and a distorted sense of time for the user. There is always a risk for a psychological dependence to occur. As a result, those who take magic mushrooms for a prolonged period of time may find that life isn’t fun or happy or interesting without it. Psilocybin is quickly converted by the body to psilocin, which has mind-altering effects similar, in some aspects, to those of LSD, mescaline, and DMT. In general, the effects include euphoria, visual and mental hallucinations, changes in perception, a distorted sense of time, and spiritual experiences, and can include possible adverse reactions such as nausea and panic attacks.

Hopkins report: “Mushrooms work by disrupting how your nerve cells and the neurotransmitter serotonin interacts throughout the brain and spinal cord. By changing the normal functioning of serotonin in the brain, mushrooms distort the way you process information and can make you hallucinate. When you hallucinate, it becomes difficult to tell the difference between fantasy and reality. You may see, feel and hear things that don’t exist. You can also have rapid and intense emotional mood swings. Such a shift in perception can be frightening and may result in panic attacks or a complete loss of contact with reality. In this state of mind, it’s easy for unexpected and dangerous – or even fatal – accidents to happen.”

Sue Visser: “Please note that these studies were done on healthy (not sick-brained) subjects under strict medical supervision. To permanently dissolve our ego Gurus like Deepak Chopra recommend meditation and mindfulness. I would add to that a detoxification protocol and adequate nourishment for the body and the brain. At the best of times our brain requires more glucose and oxygen than other tissues. We are all connected to our higher self and don’t need chemicals to facilitate communication.”

When we resonate with God we do not experience these side effects:
Adverse effects of psilocybin

• Light-headedness, dilated pupils (causes blurred vision)

• A dry mouth, sweating and increased body temperature followed by chills and shivering

• Numbness, particularly facial numbness (paresthesia)

• Exaggerated reflexes, muscle weakness and twitching

• Increased blood pressure and heart rate, nausea and vomiting

A user might also experience:

• Paranoia, confusion and disorientation

• Severe agitation, loss of coordination, loss of urinary control and convulsions

• Some people have developed prolonged psychosis resembling paranoid schizophrenia. Psychosis is a mental disorder that affects the personality and is characterized by a loss of touch with reality

Without proper psychological care, the effects can be long-lasting and harmful. A major panic attack while under the influence of the drug can lead to self-injury, suicide or other cases of acute psychosis. Suddenly and without warning, a few days or even a year later, the brain can produce flashbacks: feelings and thoughts that replay the effects of being on the drug. And because mushrooms disturb the normal functioning of the brain, it’s important to note that some long-term effects like psychiatric illness and impaired memory have been reported.

Sue: We need our brain to function without using disruptive chemicals that interfere with the healthy interaction of neurons. The main problem with taking a “substance” is that there is not a conscious decision to manage your mind by connecting to your higher self in a respectful and mindful way. You hand over your power to a dodgy drug and it has a 50:50 chance of elating or screwing with your senses. Either way, you take more of the stuff and over a period of time you need increasing amounts to generate the same effect.

What is the best way to deal with a sick mind?

Doctor James: “We can make enough serotonin throughout or lives and we can use it to good effect. All it takes is a desire to investigate what the problem is and to correct it with dietary and detoxification protocols. Serotonin is there for the taking and the only fix you need is a whopping dose of supplements that any naturopath or Doctor of integrated medicine would gladly select for you. But first you need to book in for a thorough investigation to nail the causes of your inner turmoil.”

This healing will take place if you become more physically active and improve your nutritional status. Put plainly, natural medicine resonates with your body and chemical remedies do not. Whilst alive we consume food and water from the earth; when we die, we return to the earth. As the earth consists of all the plant and animal kingdoms, it’s not hard to assume that our bodies are far more familiar with that which comes from the earth rather than substances produced in a pharmaceutical laboratory. Dr James Liddell is not saying that pharmaceutical medicines do not work – but they do have side effects, and very often while sorting out one problem, they create another.

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