Cardio vascular disease and statins 2015 opinion

healthy heart

Statins can stimulate atherosclerosis and heart failure
In contrast to the current belief that cholesterol reduction with statins decreases atherosclerosis, latest research states that statins may be causative in coronary artery calcification and can function as mitochondrial toxins that impair muscle function in the heart and blood vessels through the depletion of coenzyme Q10 and ‘heme A’, and thereby ATP generation.  Statins can inhibit the synthesis of vitamin K2, the cofactor for matrix Gla-protein activation, which in turn protects arteries from calcification.  Statins inhibit the biosynthesis of selenium containing proteins, one of which is glutathione peroxidase serving to suppress peroxidative stress.  An impairment of seleno-protein biosynthesis can be a factor in congestive heart failure, reminiscent of the dilated cardiomyopathies seen with selenium deficiency.
Heart failure and atherosclerosis that plagues the modern world may paradoxically be aggravated by the pervasive use of statin drugs.
If you are a high risk patient for cardio vascular disease and you use statins, please discuss it with your wellness doctor/specialist and consider a natural remedy like Lipostat (by Medford) or similar.

Expert Rev ClinPharmacol. 2015 Feb 6:1-11.Okuyama H1, Langsjoen PH, Hamazaki T, Ogushi Y, Hama R, Kobayashi T, Uchino H.

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